Application of Cannabis Sativa L. as a Therapeutic Alternative for Analgesia in Dental Treatments: An Integrative Literature Review

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Elaine Mel Cavalcante Silva
João Victor Menezes do Nascimento
https://orcid.org/0000-0002-0061-4024
Sarah Mendes de Sousa Macedo Silva
Gisvani Lopes de Vasconcelos

Abstract

Cannabis has a medicinal tradition and is recognized for its potential in relieving pain, especially in dental contexts. This study investigates the analgesic properties of the plant, focusing on identifying the benefits and harms associated with its use. The objective is to evaluate the effectiveness of Cannabis compounds, particularly cannabinoids, in managing orofacial pain and dental conditions. An integrative literature review was conducted with a critical analysis of selected studies from the PubMed, BVS, and Google Scholar (gray literature) databases. The results indicate that both cannabidiol (CBD) and tetrahydrocannabinol (THC) have analgesic effects, showing improvements in dental pain, oral ulcers, and temporomandibular disorders, positioning themselves as a viable alternative to traditional analgesics. The use of cannabinoids may offer relief for orofacial pain and highlights their potential as a therapeutic resource in dentistry. Furthermore, the analgesic and anti-inflammatory effects of Cannabis open new possibilities for more effective and less invasive dental treatments, suggesting a promising alternative to conventional painkillers. However, more clinical studies and regulatory adjustments in Brazil are still necessary for the safe and accessible implementation of medical Cannabis use.

Article Details

How to Cite
Application of Cannabis Sativa L. as a Therapeutic Alternative for Analgesia in Dental Treatments: An Integrative Literature Review. (2025). Brazilian Journal of Dentistry Oral Radiology, 4(1), bjd64. https://doi.org/10.52600/2965-8837.bjdor.2025.4.bjd64
Section
Review
Author Biographies

Elaine Mel Cavalcante Silva, University Center INTA – UNINTA

University Center INTA – UNINTA, Sobral, Ceará, Brazil.

João Victor Menezes do Nascimento, University Center INTA – UNINTA

University Center INTA – UNINTA, Sobral, Ceará, Brazil.

Sarah Mendes de Sousa Macedo Silva, University Center INTA – UNINTA

University Center INTA – UNINTA, Sobral, Ceará, Brazil.

Gisvani Lopes de Vasconcelos, University Center INTA – UNINTA

University Center INTA – UNINTA, Sobral, Ceará, Brazil.

How to Cite

Application of Cannabis Sativa L. as a Therapeutic Alternative for Analgesia in Dental Treatments: An Integrative Literature Review. (2025). Brazilian Journal of Dentistry Oral Radiology, 4(1), bjd64. https://doi.org/10.52600/2965-8837.bjdor.2025.4.bjd64

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