This cover page represents the editorial titled “Digital Science in Dentistry: Challenges, Innovations, and the Path Forward,” which delves into the transformative impact of digital technology on dental practices and education. The article explores cutting-edge advancements such as intraoral scanners, 3D printing, and computer-aided design and manufacturing (CAD/CAM), which have revolutionized diagnostic precision, treatment planning, and patient care. Highlighting the role of artificial intelligence (AI), the piece examines its integration into oral radiology, where AI is enhancing diagnostic capabilities and automating routine tasks, while also addressing critical issues like data privacy and ethical considerations. Furthermore, the editorial sheds light on the adoption of teledentistry, a pivotal innovation that has improved access to care and optimized treatment delivery, especially in underserved communities. The editorial underscores the challenges of incorporating these advancements, such as the need for financial investment, continuous professional development, and addressing health disparities.